Closed-Loop, Steady-State Recycling - A Powerful Chromatographic Tool for Binary Separations

Topics:
Pharmeceuticals
Tags:
GROUPE Novasep,
Productivity,
Recycling,
Separation,
Tool
Source:
GROUPE Novasep

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Overview: Compared to continuous chromatographic processes, batch processes can be characterized by there: simplicity, flexibility, limited productivity. An elegant way to increase productivity of batch chromatography (HPLC), in the case of binary separations, is to use a concept known as Steady State Recycling (SSR) and commercialized under the name Cyclojet. This concept is implemented on the NOVA SEP HIPER SEP line. The paper outlines that chiral separations are the most important type of binary separations in the pharmaceutical industry. Consequently, most of the drugs with stereogenic centers must be enantiomerically pure.

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Format: PDF | Size: 320KB | Date: Oct 2005 | Pages: 11

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