A Blue Dye for Substrate Tagging in the Two-Color Screening of Combinatorial Libraries

Topics:
Chemical
Tags:
American Chemical Society,
Screening,
Substrate,
Tagging
Source:
American Chemical Society

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Overview: Split-and-mix combinatorial chemistry has made important contributions to the study of molecular recognition. In systems for which fully rational design is unrealistic, the method allows large libraries of potential receptors or substrates to be tested in parallel. Screening is typically visual, employing colored targets that concentrate in beads bearing the most effective binding partners. Dye-labeling of targets is, therefore, an important part of the methodology.

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Format: PDF | Size: 142KB | Date: Oct 2004 | Pages: 3

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