Association Between Smaller Left Posterior Superior Temporal Gyrus Volume on Magnetic Resonance Imaging and Smaller Left Temporal P300 Amplitude in First-Episode Schizophrenia
- Topics:
- Healthcare Services
- Source:
- American Medical Association
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Overview: In chronic schizophrenia, the P300 is broadly reduced and shows a localized left temporal deficit specifically associated with reduced gray matter volume of the left posterior superior temporal gyrus (STG). In first-episode patients, a similar left temporal P300 deficit is present in schizophrenia, but not in affective psychosis. The present paper investigated whether the left temporal P300-left posterior STG volume association is selectively present in first-episode schizophrenia. The result in this paper suggest that the left temporal P300 abnormality specifically associated with left posterior STG gray matter volume reduction is present at the first hospitalization for schizophrenia but is not present at the first hospitalization for affective psychosis.
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Format: PDF | Size: 382KB | Date: Mar 2002 | Pages: 11
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