Evaluation of Methods for Predicting the Topology of Beta-Barrel Outer Membrane Proteins and a Consensus Prediction Method
- Topics:
- Chemical,
- Pharmeceuticals
- Tags:
- BioMed Central,
- Healthcare,
- Human Resources,
- Membrane Protein,
- Performance Management,
- Workforce Management
- Source:
- BioMed Central
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Overview: Prediction of the transmembrane strands and topology of beta-barrel outer membrane proteins is of interest in current bioinformatics research. The paper evaluates the performance on a non-redundant dataset of 20 beta-barrel outer membrane proteins of gram-negative bacteria, with structures known at atomic resolution. Also, it describe, for the first time, an effective way to combine the individual predictors, at will, to a single consensus prediction method.
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Format: PDF | Size: 182KB | Date: Jan 2005 | Pages: 35
