Subtree Power Analysis Finds Optimal Species for Comparative Genomics

Topics:
Pharmeceuticals
Tags:
Analysis,
Biotechnology,
Species
Source:
University of California, Berkeley

FREE Registration is required

Overview: Sequence comparison across multiple organisms aids in the detection of regions under selection. However, resource limitations require a prioritization of genomes to be sequenced. This prioritization should be grounded in two considerations: the lineal scope encompassing the biological phenomena of interest, and the optimal species within that scope for detecting functional elements. They introduce a statistical framework for optimal species subset selection, based on maximizing power to detect conserved sites. In a study of vertebrate species, they show that the optimal species subset is not in general the most evolutionarily diverged subset. Their results suggest that marsupials are prime sequencing candidates.

(Is this item miscategorized? Does it need more tags? Let us know.)

Format: PDF | Size: 1,618KB | Date: Dec 2004 | Pages: 16

Top results from Pharmeceuticals

White Paper Protecting the Public Health: FDA Pursues an Aggressive Enforcement Strategy
White Paper Genetic Manipulation in Animals: Advanced Transgenesis and Cloning
White Paper The Economics of Innovation: Global Price Controls and the Future of Biomedical R&D
White Paper Prospects for a Bioeconomy: The Biomedical Industry and Regional Economic Development
White Paper Bovine Genomic Sequencing Initiative: Cattle-Izing the Human Genome

» View all Pharmeceuticals listings

advertisement
advertisement
  • Click Here
  • Click Here
  • Click Here
advertisement

Returning users: Log In Here!

Already registered on BNET, TechRepublic, or ZDNet? Simply log in.

Free Membership: Sign Up Now!

Sign up for a free membership today and get instant and unlimited access to one of the largest databases of white papers, webcasts, and casestudies anywhere. Your FREE membership allows you to:

  • Download an unlimited amount of content, including classic and current white papers, case studies, webcasts and more
  • Track content on your chosen topics of interest
  • Receive targeted email alerts when your favorite content is added
  • Save content for future reading
  • Receive our member newsletter

When you register to access this directory, you become a member of BNET. In addition, you allow us to share your information with companies that produce products or services featured in the library--so that such companies may contact you with information and offers regarding their products and services. This enables us to keep the library a free service. As a directory registrant, you will receive a complimentary subscription to the BNET member newsletter, The BNET Report. You can unsubscribe from this newsletter at any time. By clicking the Sign up button, you indicate that you agree to our Terms and Conditions and have read and understand our Privacy Policy (updated).